Renee Frank is a graduate of the Philadelphia College of Art (now University of the Arts) in Philadelphia. She also studied at the Pennsylvania Academy of Fine Art, and at Temple University Tyler School of Art.
She worked in the fashion industry and was also a high school art teacher at Ambler High School in Pennsylvania.
As a painter, she was represented by the Joy Berman Gallery in Philadelphia, and The Philadelphia Art Museum Sales gallery.
After moving to Florida, she was represented by the Sandra Neustatter Gallery in Delray Beach. Her work is in many corporate collections and the lobby of the Chester Crozier Hospital in Pennsylvania.